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Stem cells
STEM CELLS unique cell technology (Belarus)

Stem cells

New unique methods of Mesenchymal Stem Cells (MSC) application have been developed in RSPC for Traumatology and Orthopedics.

Studies show that MSCs have high plasticity and can turn into bone, cartilage, muscle, adipose and other tissues under the control of local factors and the microenvironment at the implantation site.

Important properties of MSC for their clinical use are secretory capacity and immunomodulation. Numerous studies have determined the ability of MSCs to secrete biologically active molecules - growth factors and cytokines: VEGF, CNTF, GDNF, TGF, interleukins and ligands. These biologically active substances affect the processes of angiogenesis, chondrogenesis, inhibit inflammatory processes, have immunosuppressive properties - reduce the proliferation and activation of T-lymphocytes, as well as the production of antibodies.

Thus, MSCs can be successfully used for regenerative therapy and rehabilitation treatment of organs. The regenerating effect of MSCs is due to their structural contribution to tissue repair, as well as their immunomodulatory and anti-inflammatory effects by direct cellular interaction and secretion of bioactive factors.

MSC application is a safe procedure. Currently no cases of cancer due to MSC application ware established. Moreover, MSC don’t have HLA class II antigens, so donor cells from other humans can be safely applicated for patient treatment.

What is the uniqueness of our method? In many clinics all over the world biological minimally manipulated cell products with MSC are used. These cell products (Bone Marrow Aspirate Concentrate / Stromal Vascular Fraction from abdomen fat) contain 0,01-1% of MSC. In our clinic we use pure laboratory cultivated bone marrow MSC.

What are the advantages of expanded stem cells application?

  • Pure cell monoculture;
  • Predicted properties;
  • Higher MSC number;
  • Laboratory pre-differentiation capability into cartilage or bone direction;
  • Possibility of allogeneic (donor cells) use/

We can offer Mesenchymal stem cells application for a number of orthopedic diseases:

  • Osteoarthritis;
  • Full thickness joint cartilage lesions;
  • Femur head osteonecrosis/

All methods are approved by Ministry of Public Health of the Republic of Belarus.

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